At-Home Ketamine
Microdose Program
Physician-supervised, at-home ketamine therapy for depression, anxiety, PTSD, chronic pain, and more — available throughout California via telehealth.
A Different Approach to Ketamine Therapy
Ketamine microdosing delivers low doses of ketamine in sublingual lozenge form — small enough that you won't experience dissociative or hallucinogenic effects, but sufficient to promote the neuroplastic changes that drive lasting improvement in mood, focus, and resilience.
Unlike IV infusions, the at-home microdose program is designed for ongoing use — building cumulatively over weeks to rewire the neural pathways associated with depression, anxiety, PTSD, and chronic pain. Every prescription is managed personally by Dr. Andre Atoian — a triple board-certified physician with 15 years of ketamine experience — via telehealth, available to patients throughout California.
Enhanced Mood & Emotional Stability
Reduces symptoms of depression and anxiety, fostering a more balanced and positive daily disposition without sedation or impairment.
Improved Focus & Cognitive Clarity
Many patients report heightened mental clarity, improved problem-solving, and increased creativity — a reflection of ketamine's neuroplastic effects on the prefrontal cortex.
Reduced Stress & Fatigue
Contributes to a calmer baseline state — reducing the physiological burden of chronic stress and alleviating the fatigue that often accompanies mood and pain disorders.
Cumulative Neuroplasticity
Results build over time. Each dose contributes to a progressive strengthening of new neural connections — particularly effective for patients whose prior treatments provided only temporary relief.
Convenient At-Home Use
Lozenges are dispensed from a licensed compounding pharmacy and delivered directly to you. No clinic visits required — all care happens via telehealth, anywhere in California.
Physician-Supervised Protocol
Every prescription managed personally by Dr. Atoian — triple board-certified with 15 years of ketamine experience. Your dosage monitored and adjusted throughout your program.
Why Ketamine Works When Other Treatments Don't
Most antidepressants target serotonin — a system that takes weeks to respond and fails entirely in roughly 30–40% of patients. Ketamine works through an entirely different mechanism, offering an alternative pathway to relief for patients who have not found it through conventional treatment.
The Glutamate Pathway
Ketamine acts on NMDA receptors in the glutamate system — the brain's primary excitatory pathway. By blocking these receptors temporarily, ketamine triggers a cascade of neuroplastic changes: glutamate surges, BDNF (brain-derived neurotrophic factor) is released, and new synaptic connections form — literally regrowing the neural pathways that depression, trauma, and chronic stress have degraded.
This is why patients who have failed multiple antidepressants often respond remarkably well to ketamine therapy — it bypasses the serotonin system entirely and works at the structural level of brain function.
How the Microdose Program Works
From your initial discovery call through ongoing monitoring, every step is managed personally by Dr. Atoian via telehealth — available to patients throughout California.
Free Discovery Call
A brief introductory call to learn about your history, symptoms, and goals — and to determine whether the microdose program is the right fit before committing to a full consultation.
Initial Consultation with Dr. Atoian
A comprehensive telehealth evaluation covering your medical history, prior treatments, current medications, and goals. Dr. Atoian designs a personalized dosing protocol and submits your prescription to a licensed compounding pharmacy.
Weekly Progress Questionnaires
You complete brief weekly check-ins through our outcome monitoring system so Dr. Atoian can track your response, identify patterns, and adjust your dose if needed.
Telehealth Follow-Up Appointments
Regular virtual appointments with Dr. Atoian to review your progress, renew your prescription, and adjust your protocol as your response evolves. Most patients see meaningful improvement within 2–4 weeks.
What Ketamine Can Help With
Ketamine's mechanism of action makes it uniquely effective across a broad range of mood, trauma, and pain conditions — particularly those that have not responded to conventional treatment.
Treatment-Resistant Depression
Ketamine has a success rate of up to 70% in patients who have tried conventional antidepressants without adequate relief — working through a fundamentally different pathway where SSRIs and SNRIs have failed.
Anxiety Disorders
Microdosing has demonstrated consistent improvement in generalized anxiety, social anxiety, and panic. In our own research, 100% of patients experienced improved anxiety over a 4–6 week program.
PTSD
Ketamine disrupts the consolidation of traumatic memories and reduces hyperarousal — often providing relief from PTSD symptoms where other treatments have provided only partial benefit.
Postpartum Depression
One of the few treatments capable of acting fast enough to meaningfully support new mothers in the acute postpartum period, without the weeks-long delay of conventional antidepressants.
OCD
Ketamine has shown the ability to reduce intrusive thoughts and compulsive patterns — offering relief to patients struggling with OCD that has not responded adequately to standard pharmacological treatment.
Post-Acute Withdrawal Syndrome
For patients in recovery from addiction who are struggling with persistent depression or mood instability, ketamine offers an evidence-backed path to relief that doesn't compromise their sobriety.
Complex Regional Pain Syndrome (CRPS)
Ketamine's unique mechanism helps reset overactive pain nerves that fire inappropriately — offering meaningful relief for one of the most difficult-to-treat pain conditions in modern medicine.
Fibromyalgia
Ketamine can reduce the widespread chronic pain of fibromyalgia, particularly when conventional medications have been difficult to tolerate or have provided only partial relief.
Neuropathy & Neuralgia
Ketamine supports nerve healing and reduces overactive nerve signaling — beneficial for peripheral nerve damage, diabetic neuropathy, trigeminal neuralgia, and post-herpetic neuralgia.
Chronic Cancer Pain
For patients managing cancer-related pain with heavy opioid regimens, ketamine can be integrated into a multi-modal approach to provide better pain control while reducing opioid dependence.
Chronic Fatigue
By addressing the neurological and inflammatory components of chronic fatigue, ketamine therapy can restore energy levels and cognitive function in patients who have not found relief through conventional approaches.
Brain Fog
Ketamine's neuroplastic effects on the prefrontal cortex and hippocampus can meaningfully improve cognitive clarity, memory, and executive function — particularly when brain fog is linked to depression or chronic stress.
Burnout & Stress-Related Conditions
For high-functioning patients whose performance and well-being have been degraded by sustained stress, microdose ketamine offers a path to neurological recovery without disrupting daily functioning.
Mood Disorders (General)
Ketamine's broad neuroplastic effects make it beneficial across a range of mood disorders — including dysthymia, cyclothymia, and mood instability related to hormonal or neurological factors.
Limbic Medical's Own Clinical Data
Dr. Atoian and the Limbic Medical team led a peer-reviewed study on microdose ketamine among healthcare workers. Published in the Journal of Psychedelic Studies (2022), the results speak for themselves.
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What Our Patients Say
"Dr. Atoian is really the best. I was having a really hard time with my depression that wouldn't go away, even taking medications. I did the infusions and now I'm doing microdosing and I feel great. My anxiety is much better and my depression is pretty much gone."
"Dr. Atoian has been an absolute life saver. Thanks to Dr. Atoian and his team I've been able to get back to life. I'm extremely happy to say that after his treatments I have absolutely no pain."
"Coming here for ketamine therapy has cured me of depression, anxiety and complex PTSD. I am still in awe of how happy, calm, safe, and content I feel on a daily basis."
Frequently Asked Questions
Ready to See If Microdosing Is Right for You?
Start with a free, no-commitment discovery call. We'll learn about your history, your goals, and whether this program is a good fit — before scheduling a full consultation.
